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Bactrim – Overview Bactrim prescription medication is an antibacterial medication that is used to treat and prevent infections when the infection is suspected to be caused by bacteria susceptible to Bactrim. This medication is a combination of two antibiotics: sulfamethoxazole and trimethoprim. It is used to treat a wide variety of bacterial infections. It is also used to prevent and treat a certain type of pneumonia (pneumocystis-type). This medication treats only certain types of infections. It will not work for viral infections (such as common cold, flu). Using any antibiotic when it is not … Compare prescription drug prices on medications at more than 70,000 pharmacies and save instantly! Generic Bactrim ® Sulfamethoxazole / Trimethoprim Sulfamethoxazole/trimethoprim † is an antibiotic used to treat UTIs. 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